NAM PHUC THINH TRADING CO., LTD
TOTALMAST
Composition: Each injection contains: Cefoperazone sodium 250 mg; Excipient q.s. 10 g
Pharmaceutical form: Intramammary Ointment
Properties: Totalmast contains cefoperazone sodium, a third generation cephalosporins antibiotic to combat mastitis caused by Gram positive and Gram-negative germs. Cefoperazone is unique among third-generation cephalosporins, its use is approved in the treatment of skin infections caused by P. aeruginosa, S. aureus and S. pyogenes, in gynecological infections by bacteroids, clostridia, anaerobic cocci, E. coli, gonococci, and epidermides, Staphylococcus aureus and Streptococcus agalactiae.
Totalmast has greater ability to resist enzymes, beta-lactamases produced by a majority of pathogenic Gram positive and Gram negative bacteria, than cephalosporins of first and second generation.
Target species: lactating cattle
Indications: Totalmast is intended for lactating cattle for the treatment of acute and subacute clinical mastitis caused by:
- Staphylococcus aureus - Streptococcus dysgalactiae
- Micrococcus spp. - Escherichia coli
- Staphylococcus epidermidis - Streptococcus uberis
- Corynebacterium pyogenes - Pseudomona aeruginosa
- Streptococcus agalactiae - Streptococcus pyogenes
- Corynebacterium bovis - Klebsiella spp
Route of administration: Via intramammary, after external disinfection of the udder.
Dosage and direction for use: Previous external disinfections of the udder and drain thorougly, apply the contents of a syringe into each affected quarter; gently massage the udder treated upwards, so that the medication reaches deeper regions. Totalmast maintains its therapeutic effect for an extended period of 48 hours, a single dose is sufficient for most cases. In severe cases as chronic or systemic mastitis, subsequent doses may be required at intervals of 48 hours or according to instructions of the veterinarian.
Contraindications: Not described.
Side effects: The cephalosporins, including Totalmast, like any beta-lactam antibiotic may present sporadical allergic or anaphylactic reactions.
Overdose: Being an intramammary application specialty, poisoning by overdose is unlikely to occur because the breast tissues have a secretory character and systemic absortion is minimal. The elimination of the product is carried out by drainage during milking.
Withdrawal time: Do not consume the milk produced by the affected quarter until 4 days (7 milkings) after the last application. Food animals cannot be slaughtered until 48 hours after the last treatment.
Storage conditions and recommendations: Keep in a cool dry place, protected from light. Do not store above 30°C. Keep out of sight and reach of children and domestic animals.
Presentations: Syringe of 10 g
Shelf-life: 2 years from the manufacturing date
FOR VETERINARY USE ONLY
Keep out of the reach of children
LIVISTO S.A. DE C.V.
Carretera al puerto de la Libertad , Km 20,
Zaragoza, La Libertad, El Salvador C.A.
